Hannah Borgerson and Jordan Tilley helped Ashland inch closer in each set but ultimately the Grizzlies couldn't hang with one of the top 6A teams in the state.
Roseburg handed Ashland a straight-game loss in its regular season finale, 25-16, 25-18, 25-20, Tuesday at Mountain Avenue Gym.
Borgerson, a senior outside hitter, had 17 digs and three kills, and Tilley, a junior setter, finished with 19 assists, four kills and two blocks. Also for Ashland (6-14), Hope Baldrica had seven kills and Ellie Case five kills and two blocks.
Roseburg (23-3) has won nine of its last 10 matches.
Ashland now must wait to find out how far it will have to travel for a Class 5A play-in match to be played next week. The top eight teams in the final OSAA rankings, which freeze Saturday, automatically qualify for the 16-team state tournament. Ashland was ranked 23rd on Tuesday night.
The South Medford boys soccer team got just the tune-up it was looking for heading into Saturday's regular season finale at crosstown rival North Medford.
Jairo Carillo tallied his first hat trick of the season and Uriel Cordoba provided two assists to lead the Panthers to a 5-2 win over Ashland in nonleague action Tuesday at South Medford High School.
Carillo gave the Panthers a 2-0 halftime lead with a pair of headers, then tacked on an insurance goal in the 58th. His two first-half goals were both assisted by Uriel Cordoba, and the first was also assisted by Kyle Owings.
South Medford (7-3-2) has now won three games in a row since suffering back-to-back losses to North Medford and Grants Pass.
"It was a good match," South Medford head coach Dave Kaufmann said. "Ashland gives us heck every time we play them and this was a good shot in our arm. We had some tough games and maybe haven't performed to the ability that we could so hopefully this will get us back on track heading into our final league game (Saturday). If all goes right for the Panthers, it'll be a great end of the week for us."
For the Grizzlies (5-5-1), senior fullback Gabe Young scored two goals, first a header off an assist by senior Nick Chouard in the 61st minute, and later finishing a scramble in the box in the 67th.
Ashland coach Abdiaziz Guled credited Young, senior forward Kevin Weatherby and junior fullback David Lehrburger with leading the Grizzlies.
"Our kids didn't give up," Guled said. "They fought back and it was a good game. We tried to keep up with them but South did a good job."
Ashland travels to Crater on Saturday before wrapping up its regular season with a game against Southern Oregon Hybrid 5A rival Eagle Point, Oct. 29 at Eagle Point.